MONAI, or Medical Open Network for AI, is an open-source framework designed for deep learning in healthcare imaging. It provides robust tools and libraries for healthcare professionals, enabling them to develop, train, and deploy AI-driven solutions quickly and efficiently. Its modular architecture ensures that users can customize their workflows while leveraging existing components, leading to more efficient research and clinical collaboration. With MONAI, developers can handle diverse medical datasets, facilitating advancements in medical imaging technologies.

This open-source framework combines the AgentSimJs agent modeling library with Three.js's 3D graphics engine to deliver interactive, browser-based multi-agent simulations. Users can define agent types, behaviors, and environmental rules, configure collision detection and event handling, and visualize simulations in real time with customizable rendering options. The library supports dynamic controls, scene management, and performance tuning, making it ideal for research, education, and prototyping of complex agent-based scenarios.

MultiAgentPacman offers a Python-based game environment where users can implement, visualize, and benchmark multiple AI agents in the Pacman domain. It supports adversarial search algorithms like minimax, expectimax, alpha-beta pruning, as well as custom reinforcement learning or heuristic-based agents. The framework includes a simple GUI, command-line controls, and utilities to log game statistics and compare agent performance under competitive or cooperative scenarios.

RoboCup Rescue Agent Simulation is an open-source framework that models urban disaster environments where multiple AI-driven agents collaborate to locate and rescue victims. It offers interfaces for navigation, mapping, communication, and sensor integration. Users can script custom agent strategies, run batch experiments, and visualize agent performance metrics. The platform supports scenario configuration, logging, and result analysis to accelerate research in multi-agent systems and disaster response algorithms.

Base OnChain Agent is an open-source framework designed to deploy autonomous AI agents on Ethereum-like blockchains. It connects to blockchain nodes via Web3 and uses OpenAI's GPT models to interpret on-chain events such as token transfers or protocol-specific logs. The agent can process natural language prompts or predefined strategies to decide when to execute transactions, call smart contract functions, or respond to governance proposals. Developers can extend modules for custom event listeners, integrate off-chain data feeds, and manage private keys securely. This solution enables automated DeFi operations like liquidity provisioning, arbitrage trading, and portfolio rebalancing with minimal manual intervention.

BeeAI Framework Py Starter is an open-source Python project designed to bootstrap AI agent creation. It includes core modules for agent orchestration, a plugin system to extend functionality, and adapters for connecting to popular LLM APIs. Developers can define tasks, manage conversational memory, and integrate external tools through simple configuration files. The framework emphasizes modularity and ease of use, enabling rapid prototyping of chatbots, automated assistants, and data-processing agents without boilerplate code.

Cerebellum offers a modular platform where developers define agents using declarative plans composed of sequential steps or tool invocations. Each plan can call built-in or custom tools—such as API connectors, retrievers, or data processors—through a unified interface. Memory modules allow agents to store, retrieve, and forget information across sessions, enabling context-aware and stateful interactions. It integrates with popular LLMs (OpenAI, Hugging Face), supports custom tool registration, and features an event-driven execution engine for real-time control flow. With logging, error handling, and plugin hooks, Cerebellum boosts productivity, facilitating rapid agent development for automation, virtual assistants, and research applications.

The RAG-based Intelligent Conversational AI Agent combines a vector store-backed retrieval layer with Google’s Gemini LLM via LangChain to power context-rich, conversational knowledge extraction. Users ingest and index documents—PDFs, web pages, or databases—into a vector database. When a query is posed, the agent retrieves top relevant passages, feeds them into a prompt template, and generates concise, accurate answers. Modular components allow customization of data sources, vector stores, prompt engineering, and LLM backends. This open-source framework simplifies the development of domain-specific Q&A bots, knowledge explorers, and research assistants, delivering scalable, real-time insights from large document collections.

Trinity-RFT (Retrieval Fine-Tuning) is a unified open-source framework designed to enhance model accuracy and efficiency by combining retrieval and fine-tuning workflows. Users can prepare a corpus, build a retrieval index, and plug the retrieved context directly into training loops. It supports multi-modal retrieval for text, images, and video, integrates with popular vector stores, and offers evaluation metrics and deployment scripts for rapid prototyping and production deployment.

Autonomous Economic Agents (AEA) by Fetch.ai is a versatile framework that empowers developers to design, implement, and orchestrate autonomous software agents capable of interacting with each other, external environments, and digital ledgers. Leveraging a plugin-based architecture, AEA provides pre-built modules for communication protocols, cryptographic ledger APIs, decentralized identity, and customizable decision-making skills. Agents can discover and transact within decentralized marketplaces, perform goal-driven behaviors, and adapt through real-time data feeds. The framework supports simulation tools for testing and debugging multi-agent scenarios, as well as deployment onto live blockchains or peer-to-peer networks. With built-in interoperability and agent-to-agent messaging, AEA streamlines the development of complex autonomous economic applications such as energy trading, supply chain optimization, and smart IoT coordination.

AI-Agentic Machine Translation is an open-source framework designed for research and development in machine translation. It orchestrates three core agents—a generator, an evaluator, and a refiner—to collaboratively produce, assess, and refine translations. Built on PyTorch and transformer models, the system supports supervised pre-training, reinforcement learning optimization, and configurable agent policies. Users can benchmark on standard datasets, track BLEU scores, and extend the pipeline with custom agents or reward functions to explore agentic collaboration in translation tasks.

RAGENT is designed to create autonomous AI agents that can interact with diverse tools and data sources. Under the hood, it uses retrieval-augmented generation to fetch relevant context from local files or external sources and then composes responses via OpenAI models. Developers can plug in tools for web search, browser automation with Selenium, file read/write operations, code execution in secure sandboxes, and OCR for image text extraction. The framework manages conversation memory, handles tool orchestration, and supports custom prompt templates. With RAGENT, teams can rapidly prototype intelligent agents for document Q&A, research automation, content summarization, and end-to-end workflow automation, all within a Python environment.