CopilotKit is an open-source Python framework designed for developers to build customized AI agents. It offers a modular architecture where you can register and configure tools — such as file system access, web search, Python REPL, and SQL connectors — then wire them into agents that leverage any supported LLM. Built-in memory modules allow conversation state persistence, while LangGraph lets you define structured reasoning flows for complex tasks. Agents can be deployed in scripts, web services, or CLI apps and scale across cloud providers. CopilotKit works seamlessly with OpenAI, Azure OpenAI, and Anthropic models, empowering automated workflows, chatbots, and data analysis bots.

Duet GPT is a Python-based open source framework for orchestrating multi-agent conversations between two GPT models. You define distinct agent roles, customized with system prompts, and the framework manages turn-taking, message passing, and conversation history automatically. This cooperative structure accelerates complex task resolution, enabling comparative reasoning, critique cycles, and iterative refinement through back-and-forth exchanges. Its seamless OpenAI API integration, simple configuration, and built-in logging make it ideal for research, prototyping, and production workflows in coding assistance, decision support, and creative ideation. Developers can extend the core classes to integrate new LLM services, adjust the iterator logic, and export transcripts in JSON or Markdown formats for post-analysis.

MACL is a modular Python framework designed to simplify the creation and orchestration of multiple AI agents. It lets you define individual agents with custom skills, set up communication channels, and schedule tasks across an agent network. Agents can exchange messages, negotiate responsibilities, and adapt dynamically based on shared data. With built-in support for popular LLMs and a plugin system for extensibility, MACL enables scalable and maintainable AI workflows across domains like customer service automation, data analysis pipelines, and simulation environments.

Overeasy is a Python-based open-source framework for orchestrating LLM-driven AI agents across various domains. It provides a modular architecture to define agents, configure memory stores, and integrate external tools such as APIs, knowledge bases, and databases. Developers can connect to OpenAI, Azure, or self-hosted LLM endpoints and design dynamic workflows involving single or multiple agents. Overeasy’s orchestration engine handles task delegation, decision making, and fallback strategies, enabling robust digital workers for research, customer support, data analysis, scheduling, and more. Comprehensive documentation and example projects accelerate deployment on Linux, macOS, and Windows.

PromptMage is a Python framework that aims to streamline the development of complex, multi-step applications using large language models (LLMs). It offers a variety of features including a prompt playground, built-in version control, and an auto-generated API. Ideal for both small teams and large enterprises, PromptMage improves productivity and facilitates effective prompt testing and development. It can be deployed locally or on a server, making it accessible and manageable for diverse users.

Thufir is a Python-based open-source agent framework designed to facilitate the creation of autonomous AI agents capable of complex task planning and execution. At its core, Thufir provides a planning engine that decomposes high-level objectives into actionable steps, a memory module for storing and retrieving contextual information across sessions, and a plug-and-play tool interface allowing agents to interact with external APIs, databases, or code execution environments. Developers can leverage Thufir’s modular components to customize agent behaviors, define custom tools, manage agent state, and orchestrate multi-agent workflows. By abstracting away low-level infrastructure concerns, Thufir accelerates the development and deployment of intelligent agents for use cases like virtual assistants, workflow automation, research, and digital workers.

Agent-Squad is a modular Python framework that empowers teams to design, deploy, and run multi-agent systems for complex task execution. At its core, Agent-Squad lets users configure diverse agent profiles—such as data retrievers, summarizers, coders, and validators—that communicate through defined channels and share memory contexts. By decomposing high-level objectives into subtasks, the framework orchestrates parallel processing and leverages LLMs alongside external APIs, databases, or custom tools. Developers can specify workflows in JSON or code, monitor agent interactions, and adapt strategies dynamically using built-in logging and evaluation utilities. Common applications include automated research assistants, content generation pipelines, intelligent QA bots, and iterative code review processes. The open-source design integrates seamlessly with AWS services, enabling scalable deployments.

agent-steps is a Python step orchestration framework designed to streamline the development of AI agents by breaking complex tasks into discrete, reusable steps. Each step encapsulates a specific action—such as invoking a language model, performing data transformations, or external API calls—and can pass context to subsequent steps. The library supports synchronous and asynchronous execution, enabling scalable pipelines. Built-in logging and debugging utilities provide transparency into step execution, while its modular architecture promotes maintainability. Users can define custom step types, chain them into workflows, and integrate them easily into existing Python applications. agent-steps is suitable for building chatbots, automated data pipelines, decision support systems, and other multi-step AI-driven solutions.

AI-Agent is an extensible Python framework designed to create autonomous agents powered by OpenAI's GPT models and LangChain. It includes modules for web searching, Wikipedia lookup, calculator functions, and custom tool integrations, enabling automated research, data analysis, and script execution. Users can configure agents to plan multi-step tasks, interact with APIs, generate reports, and perform complex workflows without manual intervention, streamlining productivity across development, data science, and business processes.

ANAC-agents is a Python-based framework that centralizes multiple negotiation agent implementations for the Automated Negotiating Agents Competition (ANAC). Each agent within the repository embodies distinct strategies for utility modeling, proposal generation, concession tactics, and acceptance criteria, facilitating comparative studies and rapid prototyping. Users can define negotiation domains with custom issues and preference profiles, then simulate bilateral negotiations or tournament-style competitions across agents. The toolkit includes configuration scripts, evaluation metrics, and logging utilities to analyze negotiation dynamics. Researchers and developers can extend existing agents, test novel algorithms, or integrate external learning modules, accelerating innovation in automated bargaining and strategic decision-making under incomplete information.

Besser Agentic Framework offers a modular toolkit for defining, coordinating, and scaling AI agents. It allows you to configure agent behaviors, integrate external tools and APIs, manage agent memory and state, and monitor execution. Built on Python, it supports extensible plugin interfaces, multi-agent collaboration, and built-in logging. Developers can rapidly prototype and deploy agents for tasks like data extraction, automated research, and conversational assistants, all within a unified framework.

Chainlit is an open-source async Python framework designed to help developers build and deploy scalable Conversational AI and agentic applications rapidly. It supports integrations with popular Python libraries and frameworks to provide a seamless development experience. With Chainlit, users can create production-ready chat applications that can handle complex interactions and retain conversational context.

ChatGPT OpenAI Smart Speaker is a developer framework for building your own voice-activated AI assistant. It runs on devices like Raspberry Pi, Linux PCs, macOS, or Windows machines. Using standard Python libraries for speech recognition and text-to-speech synthesis, it listens for a wake word, captures your question, forwards it to the OpenAI ChatGPT API, and reads back responses in real time. You can extend it with custom commands, integrate smart home controls, or use it for educational voice AI demos.

ModelScope Agent provides a modular, Python‐based framework to orchestrate autonomous AI agents. It features plugin integration for external tools (APIs, databases, search), conversation memory for context preservation, and customizable agent chains to handle complex tasks such as knowledge retrieval, document processing, and decision support. Developers can configure agent roles, behaviors, and prompts, as well as leverage multiple LLM backends to optimize performance and reliability in production.

CodeFuse-muAgent is a Python-based open-source framework that orchestrates multiple autonomous AI agents to collaboratively solve complex tasks. Developers define individual agents with specialized skills—such as data processing, natural language understanding, or external API interaction—and configure communication protocols for dynamic task delegation. The framework provides centralized memory management, logging, and monitoring, while remaining model-agnostic, supporting integration with popular LLMs and custom AI models. By leveraging CodeFuse-muAgent, teams can build modular AI workflows, automate multi-step processes, and scale deployments across diverse environments. Flexible configuration files and extensible APIs enable rapid prototyping, testing, and fine-tuning, making it suitable for use cases in customer support, content generation pipelines, research assistants, and more.

CUPCAKE AGI (Composable Utilitarian Pipeline for Creative, Knowledgeable, and Evolvable Autonomous General Intelligence) is a flexible Python framework that simplifies building autonomous agents by combining language models, memory, and external tools. It offers core modules including a goal planner, a model executor, and a memory manager to retain context across interactions. Developers can extend functionality via plugins to integrate APIs, databases, or custom toolkits. CUPCAKE AGI supports both synchronous and asynchronous workflows, making it ideal for research, prototyping, and production-grade agent deployments across diverse applications.

Cyrano is an open-source Python framework and CLI for creating AI agents that orchestrate large language models and external tools through natural language prompts. Users can define custom tools (functions), configure memory and token limits, and handle callbacks. Cyrano handles parsing JSON responses from LLMs and executes specified tools in sequence. It emphasizes simplicity, modularity, and zero external dependencies, enabling developers to prototype chatbots, build automated workflows, and integrate AI capabilities into applications quickly.

Fast Reinforcement Learning is a specialized Python framework designed to accelerate the development and execution of reinforcement learning agents. It offers out-of-the-box support for popular algorithms such as PPO, A2C, DDPG and SAC, combined with high-throughput vectorized environment management. Users can easily configure policy networks, customize training loops and leverage GPU acceleration for large-scale experiments. The library’s modular design ensures seamless integration with OpenAI Gym environments, enabling researchers and practitioners to prototype, benchmark and deploy agents across a variety of control, game and simulation tasks.

defaultmodeAGENT is a Python-based framework designed to simplify the creation of intelligent agents that perform multi-step workflows autonomously. It features default-mode planning—an adaptive strategy for deciding when to explore versus exploit—alongside seamless integration of custom tools and APIs. Agents maintain conversational memory, support dynamic prompting, and offer logging for debugging. Built on top of OpenAI’s API, it allows rapid prototyping of assistants for data extraction, research, and task automation.

GenAI Job Agents is a Python-based open-source framework designed to streamline the creation and management of AI-powered job agents. Developers can define customized job types and agent behaviors using simple configuration files or Python classes. The system integrates seamlessly with OpenAI for LLM-powered reasoning and LangChain for chaining calls. Jobs can be queued, executed in parallel, and monitored through built-in logging and error-handling mechanisms. Agents can handle dynamic inputs, retry failures automatically, and produce structured results for downstream processing. With modular architecture, extensible plugins, and clear APIs, GenAI Job Agents empowers teams to automate repetitive tasks, orchestrate complex workflows, and scale AI-driven operations in production environments.